Summary
Utility of D-dimer level as an analytical marker in pediatric emergencies
Nso Roca AP, Riesco Riesco S, Benito Gutiérrez M, García Aparicio J
Affiliation of the authors
Servicio de Urgencias de Pediatría. Hospital Universitario Infantil “La Paz”. Madrid, España.
DOI
Quote
Nso Roca AP, Riesco Riesco S, Benito Gutiérrez M, García Aparicio J. Utility of D-dimer level as an analytical marker in pediatric emergencies. Emergencias. 2009;21:28-31
Summary
Objectives: To describe our experience using D-dimer levels in attending pediatric
emergencies.
Methods: For this retrospective descriptive study we reviewed all emergency patient
records in which D-dimer levels were measured in 2005 and 2006. We compiled
descriptive statistics and analyzed the association between levels of D-dimer and Creactive
protein (as a marker of inflammatory response) using a nonparametric
correlation test.
Results: Rash and fever were the main reasons for attending the emergency room. The
D-dimer level was elevated in 34.3% of the cases. D-dimer and C-reactive protein levels
were not correlated. The D-dimer level was elevated in 71% of the patients with sepsis.
Conclusions: D-dimer elevation is a nonspecific marker in certain inflammatory processes.
It is difficult to interpret, may lead to confusion, and should be read in a manner that is
consistent with the clinical context. Prospective studies are needed to provide evidence of
its utility as a marker in acute conditions in children.