Neurologic deficit following histiocytosis X
Affiliation of the authors
Lafuente Mateo M, Utande Vázquez A, Barra Quílez F. Neurologic deficit following histiocytosis X. Emergencias. 2011;23:112-4
Histiocytoses form a group of rare diseases characterized by the reactive or neoplastic
proliferation of histiocytes. An abnormal immune response may cause these
mononuclear phagocytes to proliferate generally or locally within an organ or tissue.
These diseases are currently classified in 3 broad groups: Langerhans cell histiocytosis
(histiocytosis X); non-Langerhans cell histiocytoses; and malignant histiocytic disorders
(acute monocytic leukemia, malignant histiocytosis, and lymphohistiocytosis. When
histiocytosis X affects vertebral bodies, usually following subacute lumbar or other back
pain, acute neurologic deficits may lead the patient to seek emergency care.