Neurologic deficit following histiocytosis X

Lafuente Mateo M, Utande Vázquez A, Barra Quílez F

Affiliation of the authors

Área de Medicina Intensiva. Servicio de Cuidados Intensivos. Hospital Universitario Miguel Servet. Zaragoza, Spain.



Lafuente Mateo M, Utande Vázquez A, Barra Quílez F. Neurologic deficit following histiocytosis X. Emergencias. 2011;23:112-4


Histiocytoses form a group of rare diseases characterized by the reactive or neoplastic

proliferation of histiocytes. An abnormal immune response may cause these

mononuclear phagocytes to proliferate generally or locally within an organ or tissue.

These diseases are currently classified in 3 broad groups: Langerhans cell histiocytosis

(histiocytosis X); non-Langerhans cell histiocytoses; and malignant histiocytic disorders

(acute monocytic leukemia, malignant histiocytosis, and lymphohistiocytosis. When

histiocytosis X affects vertebral bodies, usually following subacute lumbar or other back

pain, acute neurologic deficits may lead the patient to seek emergency care.


More articles by the authors

Leave a Reply

Your email address will not be published. Required fields are marked *