Summary
Recommendations for stocking and using antidotes in hospitals of varying levels of complexity
Aguilar-Salmerón R, Martínez Sánchez L, Broto-Sumalla A, Fernández de Gamarra-Martínez E, García-Peláez M, Nogué-Xarau S
Affiliation of the authors
Servicio de Farmacia, Hospital Universitari Dr. Josep Trueta, Girona, Spain. Servicio de Urgencias de Pediatría, Hospital Sant Joan de Déu, Barcelona, Spain. Servicio de Farmacia, Consorcio Sanitario de Terrassa, Terrassa, Spain. Servicio de Farmacia, Hospital de Sant Pau, Barcelona, Spain. Servicio de Farmacia, Hospital de Sabadell, Institut Universitari Parc Taulí-Universidad Autónoma de Barcelona, Sabadell, Spain. Secció de Toxicología Clínica, Área de Urgencias, Hospital Clínic, Barcelona, Spain. Grupo de Investigación “Urgencias, procesos y patologías”, IDIBAPS, Barcelona, Spain.
DOI
Quote
Aguilar-Salmerón R, Martínez Sánchez L, Broto-Sumalla A, Fernández de Gamarra-Martínez E, García-Peláez M, Nogué-Xarau S. Recommendations for stocking and using antidotes in hospitals of varying levels of complexity. Emergencias. 2016;28:45-54
Summary
The stocking of antidotes in various care settings is a subject of debate. A group of experts in hospital pharmacy and both adult and pediatric clinical toxicology was formed to review the Spanish and international literature on the subject with the aim of updating recommendations about which antidotes to stock and in what amounts in hospitals of different levels of complexity. The experts also considered the usual indications for the use of antidotes and dosing. The amount to have on hand was defined as enough to treat an adult weighing 70 kg for 24 hours (or 3 such adults in an A-level hospital; ie, a highly complex center or the reference hospital for an area). The group also listed 34 antidotes that B-level hospitals should stock and 22 that other types of hospital should stock. The recommendations also
provide a guide for using the antidotes in the forms of presentation available in Spain in 2015, a list of their main indications and recommended doses, and specific notes on each.