Clinical findings, risk factors, and final outcome in patients diagnosed with pulmonary thromboembolism and COVID-19 in hospital emergency departments
Jiménez Hernández S, Lozano Polo L, Suñen Cuquerella G, Peña Pardo B, Espinosa B, Cardozo C, Aguirre Tejedo A, Llorens Soriano P, Miró O
Affiliation of the authors
Area de Urgencias, Hospital Clínic. Grupo UPyP, Área 1, IDIBAPS, Barcelona, Spain. Servicio de Urgencias, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain. Servicio de Medicina Interna, Hospital del Mar, Barcelona, Spain. Servicio de Urgencias, Hospital General de Alicante, Universidad Miguel Hernández, Elche, Alicante, Spain. Servicio de Urgencias, Hospital del Mar, Barcelona, Spain..
Jiménez Hernández S, Lozano Polo L, Suñen Cuquerella G, Peña Pardo B, Espinosa B, Cardozo C, et al. Clinical findings, risk factors, and final outcome in patients diagnosed with pulmonary thromboembolism and COVID-19 in hospital emergency departments. Emergencias. 2020;32:253-7
Summary
Objective.
To analyze clinical, laboratory, and radiologic findings and final health outcomes in patients with pulmonary embolism and coronavirus disease 2019 (COVID-19). To compare them to findings and outcomes in patients with pulmonary embolism without COVID-19.
Methods.
Multicenter, observational, retrospective study in 4 Spanish hospital emergency departments (EDs) from January 15 to April 15, 2020. Cases were located by reviewing all ED requests for pulmonary computed tomography angiography (CTA) procedures. Clinical, laboratory, and radiologic findings; medical histories and comorbidity; risk factors; and outcomes were compared between the 2 groups of patients (with or without COVID-19).
Results.
A total of 399 CTAs were ordered; 88 pulmonary embolisms were diagnosed, 28 of them (32%) in patients with COVID-19. This group had more men, and a history of thromboembolic disease was more common. We found no between-group differences in clinical presentation, laboratory, or radiologic findings; nor were there differences in
final outcomes. In-hospital mortality was 7% (2 cases) in patients with COVID-19 and 17% (10 cases) in patients without the virus (odds ratio for death in patients with pulmonary embolism and COVID-19, 0.38; 95% CI, 0.08–1.89).
Conclusions.
We found no clinically important differences in the clinical, laboratory, or radiologic findings between patients with or without COVID-19 who were treated for pulmonary embolism in our hospital EDs. Final outcomes also did not differ.
